Tspan18 | tetraspanin 18

GeneMGI:1917186Synonyms: 2610042G18Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

15 No significant impact

7 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
46Embryo tissues

Phenotypes

increased mean corpuscular hemoglobin1 supporting datasetTspan18tm1.1(KOMP)VlcghomozygoteEarly adult4.59x10-6 
decreased circulating glucose level1 supporting datasetTspan18tm1.1(KOMP)VlcghomozygoteEarly adult1.25x10-5 
increased fasting circulating glucose level1 supporting datasetTspan18tm1.1(KOMP)VlcghomozygoteEarly adult3.22x10-6 
increased circulating alanine transaminase level1 supporting datasetTspan18tm1.1(KOMP)VlcghomozygoteEarly adult3.71x10-8 
decreased circulating serum albumin level1 supporting datasetTspan18tm1.1(KOMP)VlcghomozygoteEarly adult8.74x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tspan18tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Tspan18tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Tspan18tm95245(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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