Cad | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

GeneMGI:1916969Synonyms: 2410008J01Rik

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Nervous system Behavior/neurological Mortality/aging

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased prepulse inhibition	2 supporting datasets	Cad^em1(IMPC)Mbp	heterozygote	Early adult	2.79x10^-5
limb grasping	1 supporting dataset	Cad^em1(IMPC)Mbp	heterozygote	Early adult	2.7x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Cad^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Cad^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cad.

Associated images

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Histopathology

There is no histopathology data found for Cad.

IMPC related publications

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External links

No external links available for Cad.

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*Cad^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Cad^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Cad^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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