Trip13 | thyroid hormone receptor interactor 13

GeneMGI:1916966Synonyms: 2410002G23Rik, D13Ertd328e

Physiological systems

18 / 24 physiological systems tested

13 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Pigmentation Immune system Integument Adipose tissue Growth/size/body region Limbs/digits/tail Vision/eye Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

5 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:30Significant phenotypes

4Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:

Life Stage:



decreased bone mineral content	2 supporting datasets	Trip13^em1(IMPC)J	homozygote	Early adult	6.56x10^-6
male infertility	1 supporting dataset	Trip13^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased leukocyte cell number	1 supporting dataset	Trip13^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	3.8x10^-6
decreased hemoglobin content	1 supporting dataset	Trip13^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.6x10^-5
abnormal tail morphology	2 supporting datasets	Trip13^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.18x10^-5
decreased lean body mass	1 supporting dataset	Trip13^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	7.36x10^-6
decreased bone mineral density	1 supporting dataset	Trip13^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	1.61x10^-8
decreased grip strength	2 supporting datasets	Trip13^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	8.33x10^-8
hyperactivity	1 supporting dataset	Trip13^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.08x10^-7
abnormal coat/hair pigmentation	1 supporting dataset	Trip13^{tm1.1(KOMP)Vlcg}	homozygote	Late adult	4.41x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Trip13.

Associated images

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Histopathology

There is no histopathology data found for Trip13.

IMPC related publications

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External links

No external links available for Trip13.

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*Trip13^em1(IMPC)J*	Exon Deletion	‌	mouse
*Trip13^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Trip13^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Trip13^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Trip13^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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