Pof1b | premature ovarian failure 1B
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Liver/biliary system Renal/urinary system
16 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
small kidney | 1 supporting dataset | Pof1bem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
increased circulating calcium level | 1 supporting dataset | Pof1bem1(IMPC)Mbp | homozygote | Early adult | 3.17x10-5 | ||
abnormal skin morphology | 1 supporting dataset | Pof1bem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
small liver | 1 supporting dataset | Pof1bem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
abnormal kidney morphology | 1 supporting dataset | Pof1bem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
abnormal liver morphology | 1 supporting dataset | Pof1bem1(IMPC)Mbp | homozygote | Early adult | N/A * |
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External links
No external links available for Pof1b.
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Pof1bem1(IMPC)Mbp | Exon Deletion | | mouse |
Pof1btm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Pof1btm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |