Hddc2 | HD domain containing 2

GeneMGI:1916942Synonyms: 2310057G13Rik

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased lymphocyte cell number1 supporting datasetHddc2em1(IMPC)HhomozygoteEarly adult8.39x10-10 
decreased hemoglobin content1 supporting datasetHddc2em1(IMPC)HhomozygoteEarly adult1.83x10-5 
increased neutrophil cell number2 supporting datasetsHddc2em1(IMPC)HhomozygoteEarly adult3.94x10-9 
increased basophil cell number1 supporting datasetHddc2em1(IMPC)HhomozygoteEarly adult3.21x10-5 
hyperactivity4 supporting datasetsHddc2em1(IMPC)HhomozygoteEarly adult5.77x10-5 
increased circulating creatinine level1 supporting datasetHddc2em1(IMPC)HhomozygoteEarly adult6.16x10-7 
decreased erythrocyte cell number1 supporting datasetHddc2em1(IMPC)HhomozygoteEarly adult1.58x10-6 
decreased circulating fructosamine level1 supporting datasetHddc2em1(IMPC)HhomozygoteEarly adult5.38x10-7 
increased blood urea nitrogen level1 supporting datasetHddc2em1(IMPC)HhomozygoteEarly adult2.35x10-7 
decreased circulating serum albumin level1 supporting datasetHddc2em1(IMPC)HhomozygoteEarly adult4.68x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hddc2em1(IMPC)HExon Deletionmouse
Hddc2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Hddc2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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