Hddc2 | HD domain containing 2

GeneMGI:1916942Synonyms: 2310057G13Rik

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased lymphocyte cell number	1 supporting dataset	Hddc2^em1(IMPC)H	homozygote	Early adult	8.39x10^-10
decreased hemoglobin content	1 supporting dataset	Hddc2^em1(IMPC)H	homozygote	Early adult	1.83x10^-5
increased neutrophil cell number	2 supporting datasets	Hddc2^em1(IMPC)H	homozygote	Early adult	3.94x10^-9
increased basophil cell number	1 supporting dataset	Hddc2^em1(IMPC)H	homozygote	Early adult	3.21x10^-5
hyperactivity	4 supporting datasets	Hddc2^em1(IMPC)H	homozygote	Early adult	5.77x10^-5
increased circulating creatinine level	1 supporting dataset	Hddc2^em1(IMPC)H	homozygote	Early adult	6.16x10^-7
decreased erythrocyte cell number	1 supporting dataset	Hddc2^em1(IMPC)H	homozygote	Early adult	1.58x10^-6
decreased circulating fructosamine level	1 supporting dataset	Hddc2^em1(IMPC)H	homozygote	Early adult	5.38x10^-7
increased blood urea nitrogen level	1 supporting dataset	Hddc2^em1(IMPC)H	homozygote	Early adult	2.35x10^-7
decreased circulating serum albumin level	1 supporting dataset	Hddc2^em1(IMPC)H	homozygote	Early adult	4.68x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hddc2.

Associated images

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Histopathology

There is no histopathology data found for Hddc2.

IMPC related publications

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External links

No external links available for Hddc2.

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*Hddc2^em1(IMPC)H*	Exon Deletion	‌	mouse
*Hddc2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Hddc2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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