Emc10 | ER membrane protein complex subunit 10

GeneMGI:1916933Synonyms: 2310044H10Rik, 5430410O10Rik, +1 more

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Cardiovascular system

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



abnormal vocalization	1 supporting dataset	Emc10^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.06x10^-6
decreased fasting circulating glucose level	1 supporting dataset	Emc10^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	4.09x10^-6
abnormal gait	1 supporting dataset	Emc10^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.4x10^-12
thin ventricular wall	1 supporting dataset	Emc10^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	8.32x10^-5
abnormal locomotor behavior	1 supporting dataset	Emc10^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.41x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Emc10.

Associated images

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Histopathology

There is no histopathology data found for Emc10.

IMPC related publications

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External links

No external links available for Emc10.

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*Emc10^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Emc10^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Emc10^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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