Sec24d | SEC24 homolog D, COPII coat complex component

GeneMGI:1916858Synonyms: LOC383951, 2310020L09Rik

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Digestive/alimentary Liver/biliary system Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Sec24d^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*
impaired glucose tolerance	1 supporting dataset	Sec24d^{em1(IMPC)Rbrc}	heterozygote	Early adult	5.79x10^-10
abnormal liver morphology	1 supporting dataset	Sec24d^{em1(IMPC)Rbrc}	heterozygote	Early adult	N/A ^*
abnormal stomach morphology	1 supporting dataset	Sec24d^{em1(IMPC)Rbrc}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sec24d.

Associated images

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Histopathology

There is no histopathology data found for Sec24d.

IMPC related publications

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External links

No external links available for Sec24d.

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*Sec24d^{em1(IMPC)Rbrc}*	Exon Deletion	‌	mouse
*Sec24d^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Sec24d^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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