Pcgf3 | polycomb group ring finger 3
Physiological systems
16 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Embryo Growth/size/body region Limbs/digits/tail Nervous system Digestive/alimentary Vision/eye Behavior/neurological Mortality/aging Craniofacial
7 No significant impact
8 Not tested
Data collections
Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| cleft palate | 1 supporting dataset | Pcgf3em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Pcgf3em1(IMPC)Bay | homozygote | Early adult | N/A * | ||
| abnormal tail morphology | 1 supporting dataset | Pcgf3em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| decreased prepulse inhibition | 2 supporting datasets | Pcgf3em1(IMPC)Bay | heterozygote | Early adult | 5.47x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Pcgf3em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| polydactyly | 1 supporting dataset | Pcgf3em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| hyperactivity | 2 supporting datasets | Pcgf3em1(IMPC)Bay | heterozygote | Early adult | 2.78x10-5 | ||
| facial cleft | 1 supporting dataset | Pcgf3em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| syndactyly | 1 supporting dataset | Pcgf3em1(IMPC)Bay | homozygote | E18.5 | N/A * | ||
| abnormal facial morphology | 2 supporting datasets | Pcgf3em1(IMPC)Bay | homozygote | E18.5 | N/A * |
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External links
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| Pcgf3em1(IMPC)Bay | Exon Deletion | | mouse |
| Pcgf3tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Pcgf3tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |