Nup35 | nucleoporin 35

GeneMGI:1916732Synonyms: 2310006I24Rik, 5330402E05Rik

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Digestive/alimentary Behavior/neurological Mortality/aging

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased grip strength1 supporting datasetNup35tm1b(EUCOMM)WtsiheterozygoteEarly adult7.58x10-5 
enlarged cecum1 supporting datasetNup35tm1b(EUCOMM)WtsiheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetNup35tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nup35tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Nup35tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Nup35tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Nup35tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Nup35tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Nup35tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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