Prss21 | serine protease 21

GeneMGI:1916698Synonyms: testisin, 1700023E12Rik, +2 more

Physiological systems

22 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Skeleton Cardiovascular system Mortality/aging

14 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal heart morphology	1 supporting dataset	Prss21^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Prss21^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Prss21^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
kyphosis	1 supporting dataset	Prss21^{em1(IMPC)Ccpcz}	heterozygote	Early adult	9.66x10^-6
enlarged thymus	1 supporting dataset	Prss21^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
hydrometra	1 supporting dataset	Prss21^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
lordosis	1 supporting dataset	Prss21^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.56x10^-5
abnormal uterus morphology	1 supporting dataset	Prss21^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal spine curvature	1 supporting dataset	Prss21^{em1(IMPC)Ccpcz}	heterozygote	Early adult	2.28x10^-5
enlarged heart	1 supporting dataset	Prss21^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prss21.

Associated images

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Histopathology

There is no histopathology data found for Prss21.

IMPC related publications

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External links

No external links available for Prss21.

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*Prss21^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Prss21^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Prss21^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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