Fam110b | family with sequence similarity 110, member B

GeneMGI:1916593Synonyms: 1700012H17Rik

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Behavior/neurological Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased blood urea nitrogen level1 supporting datasetFam110btm1e(EUCOMM)WtsiheterozygoteEarly adult2.35x10-5 
increased hematocrit1 supporting datasetFam110btm1e(EUCOMM)WtsiheterozygoteEarly adult2.15x10-5 
abnormal response to tactile stimuli1 supporting datasetFam110btm1e(EUCOMM)WtsiheterozygoteEarly adult5.68x10-5 
preweaning lethality, complete penetrance1 supporting datasetFam110btm1e(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased circulating free fatty acids level1 supporting datasetFam110btm1e(EUCOMM)WtsiheterozygoteEarly adult7.83x10-6 
increased erythrocyte cell number1 supporting datasetFam110btm1e(EUCOMM)WtsiheterozygoteEarly adult5.03x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fam110btm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Fam110btm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Fam110btm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
mouse

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