Kctd5 | potassium channel tetramerisation domain containing 5

GeneMGI:1916509Synonyms: 2610030N08Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

embryonic lethality prior to tooth bud stage1 supporting datasetKctd5em1(IMPC)JhomozygoteE12.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetKctd5em1(IMPC)JhomozygoteEarly adultN/A * 
decreased circulating calcium level1 supporting datasetKctd5em1(IMPC)JheterozygoteEarly adult3.11x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kctd5em1(IMPC)JExon Deletionmouse
Kctd5tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Kctd5tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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