Zfp746 | zinc finger protein 746

GeneMGI:1916478Synonyms: 2810407L07Rik

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Reproductive system Pigmentation Integument Endocrine/exocrine gland Adipose tissue Growth/size/body region Skeleton

11 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased total body fat amount1 supporting datasetZfp746tm1b(EUCOMM)HmguhomozygoteLate adult4.22x10-6 
decreased bone mineral content2 supporting datasetsZfp746tm1b(EUCOMM)HmguhomozygoteLate adult8.1x10-8 
abnormal coat/hair pigmentation2 supporting datasetsZfp746tm1b(EUCOMM)HmguhomozygoteLate adult2.49x10-5 
enlarged seminal vesicle1 supporting datasetZfp746tm1b(EUCOMM)HmguhomozygoteLate adultN/A * 
decreased bone mineral density1 supporting datasetZfp746tm1b(EUCOMM)HmguhomozygoteLate adult3.71x10-7 
decreased lean body mass1 supporting datasetZfp746tm1b(EUCOMM)HmguhomozygoteLate adult2.57x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp746tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Zfp746tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Zfp746tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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