Selenot | selenoprotein T

GeneMGI:1916477Synonyms: Selt, 5730408P04Rik, +2 more

Physiological systems

14 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Integument Growth/size/body region Nervous system Behavior/neurological Skeleton Cardiovascular system

6 No significant impact

10 Not tested

Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased brain size1 supporting datasetSelenotem1(IMPC)MbphomozygoteEarly adultN/A * 
decreased locomotor activity2 supporting datasetsSelenotem1(IMPC)MbphomozygoteEarly adult3.75x10-5 
small testis1 supporting datasetSelenotem1(IMPC)MbphomozygoteEarly adultN/A * 
prolonged RR interval1 supporting datasetSelenotem1(IMPC)MbphomozygoteEarly adult2.24x10-13 
abnormal testis morphology1 supporting datasetSelenotem1(IMPC)MbphomozygoteEarly adultN/A * 
decreased startle reflex1 supporting datasetSelenotem1(IMPC)MbphomozygoteEarly adult8.04x10-5 
decreased body length1 supporting datasetSelenotem1(IMPC)MbphomozygoteEarly adult8.87x10-9 
abnormal skin morphology1 supporting datasetSelenotem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal brain morphology1 supporting datasetSelenotem1(IMPC)MbphomozygoteEarly adultN/A * 
decreased heart rate1 supporting datasetSelenotem1(IMPC)MbphomozygoteEarly adult2.63x10-12 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Selenotem1(IMPC)MbpExon Deletionmouse
Selenottm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Selenottm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Selenottm40448(L1L2_st2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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