Srsf11 | serine and arginine-rich splicing factor 11
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Nervous system Mortality/aging Cardiovascular system
17 No significant impact
4 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Srsf11tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| increased heart rate variability | 1 supporting dataset | Srsf11tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 2.55x10-6 | ||
| decreased prepulse inhibition | 1 supporting dataset | Srsf11tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 8.43x10-16 | ||
| cardiovascular system phenotype | 1 supporting dataset | Srsf11tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 5.59x10-6 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Srsf11tm1b(EUCOMM)Wtsi | homozygote | E9.5 | N/A * |
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External links
No external links available for Srsf11.
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| Srsf11tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Srsf11tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Srsf11tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Srsf11tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |