Tmem256 | transmembrane protein 256

GeneMGI:1916436Synonyms: 1810027O10Rik, 3110009M16Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Limbs/digits/tail Hematopoietic system Behavior/neurological Skeleton Cardiovascular system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



short tibia	1 supporting dataset	Tmem256^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	9.45x10^-11
abnormal vocalization	1 supporting dataset	Tmem256^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.02x10^-5
abnormal bone structure	1 supporting dataset	Tmem256^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.4x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Tmem256^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.85x10^-9
shortened ST segment	1 supporting dataset	Tmem256^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.89x10^-5
increased monocyte cell number	1 supporting dataset	Tmem256^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.92x10^-9
decreased hematocrit	1 supporting dataset	Tmem256^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.07x10^-5
decreased hemoglobin content	1 supporting dataset	Tmem256^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.57x10^-5
shortened PR interval	1 supporting dataset	Tmem256^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.53x10^-5
limb grasping	1 supporting dataset	Tmem256^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	7.39x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmem256.

Associated images

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Histopathology

There is no histopathology data found for Tmem256.

IMPC related publications

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External links

No external links available for Tmem256.

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*Tmem256^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Tmem256^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Tmem256^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tmem256^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Tmem256^{tm213330(L1L2_Bact_P)}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector
*Tmem256^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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