Snx5 | sorting nexin 5

GeneMGI:1916428Synonyms: 1810032P22Rik, D2Ertd52e, +1 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Skeleton Mortality/aging

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:90Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



decreased blood urea nitrogen level	1 supporting dataset	Snx5^Snx5	homozygote	Early adult	6.58x10^-5
decreased circulating glucose level	1 supporting dataset	Snx5^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.7x10^-6
decreased circulating potassium level	1 supporting dataset	Snx5^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.33x10^-5
decreased circulating iron level	1 supporting dataset	Snx5^Snx5	homozygote	Early adult	5.54x10^-7
decreased circulating glucose level	1 supporting dataset	Snx5^Snx5	homozygote	Early adult	7.84x10^-5
abnormal vertebrae morphology	1 supporting dataset	Snx5^Snx5	homozygote	Early adult	7.31x10^-8
increased hemoglobin content	1 supporting dataset	Snx5^Snx5	homozygote	Early adult	2.43x10^-6
decreased hematocrit	1 supporting dataset	Snx5^Snx5	homozygote	Early adult	4.46x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Snx5^Snx5	homozygote	Early adult	N/A ^*
decreased mean corpuscular volume	1 supporting dataset	Snx5^Snx5	homozygote	Early adult	5.03x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Snx5.

Associated images

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Histopathology

There is no histopathology data found for Snx5.

IMPC related publications

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External links

No external links available for Snx5.

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*Snx5^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Snx5^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Snx5^{tm296121(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Snx5^{tm35262(pL1L2_GT0_DelLacZ_bsd)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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