Ascc1 | activating signal cointegrator 1 complex subunit 1

GeneMGI:1916340Synonyms: 1810015P09Rik, ASC1p50, +1 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Growth/size/body region Vision/eye Mortality/aging Cardiovascular system

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



thick ventricular wall	1 supporting dataset	Ascc1^em1(IMPC)Bay	heterozygote	Early adult	4.01x10^-5
abnormal body wall morphology	1 supporting dataset	Ascc1^em1(IMPC)Bay	homozygote	E18.5	N/A ^*
preweaning lethality, incomplete penetrance	3 supporting datasets	Ascc1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
increased cornea thickness	1 supporting dataset	Ascc1^em1(IMPC)Bay	heterozygote	Early adult	5.1x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ascc1.

Associated images

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Histopathology

There is no histopathology data found for Ascc1.

IMPC related publications

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External links

No external links available for Ascc1.

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*Ascc1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Ascc1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ascc1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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