Gmppa | GDP-mannose pyrophosphorylase A
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Nervous system Vision/eye Behavior/neurological
12 No significant impact
7 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| impaired cued conditioning behavior | 1 supporting dataset | Gmppaem1(IMPC)Tcp | homozygote | Early adult | 6.94x10-7 | ||
| hyperactivity | 4 supporting datasets | Gmppaem1(IMPC)Tcp | homozygote | Early adult | 4.4x10-9 | ||
| impaired contextual conditioning behavior | 1 supporting dataset | Gmppaem1(IMPC)Tcp | homozygote | Early adult | 8.75x10-8 | ||
| cornea opacity | 1 supporting dataset | Gmppaem1(IMPC)Tcp | homozygote | Early adult | 2.49x10-5 | ||
| increased blood urea nitrogen level | 1 supporting dataset | Gmppaem1(IMPC)Tcp | homozygote | Early adult | 7.29x10-5 | ||
| increased vertical activity | 1 supporting dataset | Gmppaem1(IMPC)Tcp | homozygote | Early adult | 1.29x10-7 | ||
| enlarged lymph nodes | 1 supporting dataset | Gmppaem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| decreased prepulse inhibition | 1 supporting dataset | Gmppaem1(IMPC)Tcp | homozygote | Early adult | 5.58x10-5 |
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External links
No external links available for Gmppa.
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| Gmppaem1(IMPC)Tcp | Inter-exon deletion | | mouse |
| Gmppatm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |