Prrt2 | proline-rich transmembrane protein 2

GeneMGI:1916267Synonyms: 1500031I19Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Limbs/digits/tail Behavior/neurological Skeleton

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
10Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased startle reflex1 supporting datasetPrrt2tm1b(KOMP)WtsihomozygoteEarly adult1.15x10-5 
abnormal cued conditioning behavior1 supporting datasetPrrt2tm1b(KOMP)WtsihomozygoteEarly adult1.4x10-7 
increased circulating amylase level1 supporting datasetPrrt2tm1a(KOMP)WtsihomozygoteEarly adult1.7x10-9 
short tibia1 supporting datasetPrrt2tm1b(KOMP)WtsihomozygoteEarly adult6.15x10-6 
decreased circulating alkaline phosphatase level1 supporting datasetPrrt2tm1b(KOMP)WtsihomozygoteEarly adult5.64x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Prrt2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Prrt2tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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