Prpf31 | pre-mRNA processing factor 31

GeneMGI:1916238Synonyms: 2810404O06Rik, 1500019O16Rik, +2 more

Physiological systems

13 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Mortality/aging

10 No significant impact

11 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Prpf31^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased lean body mass	1 supporting dataset	Prpf31^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	6.76x10^-8
increased total body fat amount	2 supporting datasets	Prpf31^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.28x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prpf31.

Associated images

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Histopathology

There is no histopathology data found for Prpf31.

IMPC related publications

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External links

No external links available for Prpf31.

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*Prpf31^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Prpf31^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Prpf31^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Prpf31^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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