Rint1 | RAD50 interactor 1

GeneMGI:1916233Synonyms: 1500019C06Rik, 2810450M21Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased circulating calcium level	1 supporting dataset	Rint1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	4.8x10^-11
embryonic lethality prior to organogenesis	1 supporting dataset	Rint1^{tm1b(KOMP)Wtsi}	homozygote	E9.5	N/A ^*
increased circulating bilirubin level	1 supporting dataset	Rint1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	4.23x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Rint1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating glucose level	1 supporting dataset	Rint1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	6.87x10^-8
embryonic lethality prior to tooth bud stage	1 supporting dataset	Rint1^{tm1b(KOMP)Wtsi}	homozygote	E12.5	N/A ^*
decreased circulating serum albumin level	1 supporting dataset	Rint1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	4.81x10^-5
decreased circulating total protein level	1 supporting dataset	Rint1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	4.27x10^-5
decreased circulating free fatty acids level	1 supporting dataset	Rint1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	3.48x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rint1.

Associated images

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Histopathology

There is no histopathology data found for Rint1.

IMPC related publications

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External links

No external links available for Rint1.

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*Rint1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rint1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rint1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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