Dcaf12 | DDB1 and CUL4 associated factor 12
Physiological systems
21 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Immune system Hematopoietic system Behavior/neurological
18 No significant impact
3 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased neutrophil cell number | 1 supporting dataset | Dcaf12em1(IMPC)Ccpcz | homozygote | Early adult | 7.91x10-5 | ||
| decreased CD8-positive, naive alpha-beta T cell number | 1 supporting dataset | Dcaf12em1(IMPC)Ccpcz | homozygote | Early adult | 3.29x10-5 | ||
| increased effector memory T-helper cell number | 1 supporting dataset | Dcaf12em1(IMPC)Ccpcz | homozygote | Early adult | 1.78x10-5 | ||
| decreased exploration in new environment | 1 supporting dataset | Dcaf12em1(IMPC)Ccpcz | homozygote | Early adult | 4.68x10-8 | ||
| decreased lymphocyte cell number | 1 supporting dataset | Dcaf12em1(IMPC)Ccpcz | homozygote | Early adult | 4.21x10-5 | ||
| increased aggression | 1 supporting dataset | Dcaf12em1(IMPC)Ccpcz | homozygote | Early adult | 2.04x10-7 |
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External links
No external links available for Dcaf12.
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| Dcaf12em1(IMPC)Ccpcz | Exon Deletion | | mouse |
| Dcaf12tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
| Dcaf12tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |