Dcaf12 | DDB1 and CUL4 associated factor 12

GeneMGI:1916220Synonyms: 5830424K06Rik, Wdr40a, +1 more

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Hematopoietic system Behavior/neurological

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased neutrophil cell number1 supporting datasetDcaf12em1(IMPC)CcpczhomozygoteEarly adult7.91x10-5 
decreased CD8-positive, naive alpha-beta T cell number1 supporting datasetDcaf12em1(IMPC)CcpczhomozygoteEarly adult3.29x10-5 
increased effector memory T-helper cell number1 supporting datasetDcaf12em1(IMPC)CcpczhomozygoteEarly adult1.78x10-5 
decreased exploration in new environment1 supporting datasetDcaf12em1(IMPC)CcpczhomozygoteEarly adult4.68x10-8 
decreased lymphocyte cell number1 supporting datasetDcaf12em1(IMPC)CcpczhomozygoteEarly adult4.21x10-5 
increased aggression1 supporting datasetDcaf12em1(IMPC)CcpczhomozygoteEarly adult2.04x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dcaf12em1(IMPC)CcpczExon Deletionmouse
Dcaf12tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Dcaf12tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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