Ctc1 | CTS telomere maintenance complex component 1

GeneMGI:1916214Synonyms: 1500010J02Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Nervous system Mortality/aging

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased prepulse inhibition3 supporting datasetsCtc1tm1b(KOMP)WtsiheterozygoteEarly adult6.51x10-6 
preweaning lethality, complete penetrance1 supporting datasetCtc1tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ctc1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ctc1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Ctc1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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