Chst8 | carbohydrate sulfotransferase 8

GeneMGI:1916197Synonyms: 1500011J21Rik, GalNAc4ST-1

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Vision/eye Behavior/neurological

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

1Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal vibrissa morphology	1 supporting dataset	Chst8^{tm1b(KOMP)Mbp}	homozygote	Early adult	1.16x10^-5
decreased locomotor activity	4 supporting datasets	Chst8^{tm1b(KOMP)Mbp}	homozygote	Early adult	1.92x10^-7
decreased thigmotaxis	2 supporting datasets	Chst8^{tm1b(KOMP)Mbp}	homozygote	Early adult	2.31x10^-15
increased circulating alanine transaminase level	1 supporting dataset	Chst8^{tm1b(KOMP)Mbp}	homozygote	Early adult	4.44x10^-7
abnormal eye morphology	1 supporting dataset	Chst8^{tm1b(KOMP)Mbp}	homozygote	Early adult	N/A ^*
abnormal behavior	1 supporting dataset	Chst8^{tm1b(KOMP)Mbp}	homozygote	Early adult	2.32x10^-15

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Chst8.

Associated images

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Histopathology

There is no histopathology data found for Chst8.

IMPC related publications

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External links

No external links available for Chst8.

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*Chst8^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Chst8^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Chst8^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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