Vars2 | valyl-tRNA synthetase 2, mitochondrial

GeneMGI:1916165Synonyms: Vars2l, 1190004I24Rik

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Growth/size/body region Vision/eye Mortality/aging Cardiovascular system

17 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased cardiac output	1 supporting dataset	Vars2^em1(IMPC)Bay	heterozygote	Early adult	6.55x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Vars2^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal body wall morphology	1 supporting dataset	Vars2^em1(IMPC)Bay	homozygote	E18.5	N/A ^*
abnormal eye anterior chamber depth	1 supporting dataset	Vars2^em1(IMPC)Bay	heterozygote	Early adult	3.83x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Vars2.

Associated images

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Histopathology

There is no histopathology data found for Vars2.

IMPC related publications

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External links

No external links available for Vars2.

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*Vars2^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Vars2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Vars2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes