Pygo2 | pygopus 2

GeneMGI:1916161Synonyms: mpygo2, 1190004M21Rik

Physiological systems

21 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Limbs/digits/tail Nervous system Vision/eye Cardiovascular system Mortality/aging Craniofacial Renal/urinary system

12 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

29Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal hindbrain morphology	1 supporting dataset	Pygo2^{tm1b(EUCOMM)Wtsi}	homozygote	E12.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Pygo2^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
edema	1 supporting dataset	Pygo2^{tm1b(EUCOMM)Wtsi}	homozygote	E15.5	N/A ^*
abnormal neural tube closure	1 supporting dataset	Pygo2^{tm1b(EUCOMM)Wtsi}	homozygote	E12.5	N/A ^*
hemorrhage	1 supporting dataset	Pygo2^{tm1b(EUCOMM)Wtsi}	homozygote	E15.5	N/A ^*
persistence of hyaloid vascular system	1 supporting dataset	Pygo2^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.27x10^-5
abnormal midbrain morphology	1 supporting dataset	Pygo2^{tm1b(EUCOMM)Wtsi}	homozygote	E12.5	N/A ^*
abnormal limb morphology	1 supporting dataset	Pygo2^{tm1b(EUCOMM)Wtsi}	homozygote	E15.5	N/A ^*
anophthalmia	1 supporting dataset	Pygo2^{tm1b(EUCOMM)Wtsi}	homozygote	E15.5	N/A ^*
microphthalmia	1 supporting dataset	Pygo2^{tm1b(EUCOMM)Wtsi}	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Pygo2.

Associated images

Loading...

Histopathology

There is no histopathology data found for Pygo2.

IMPC related publications

Loading...

External links

No external links available for Pygo2.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Pygo2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Pygo2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pygo2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pygo2^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Pygo2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Pygo2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes