Rnf208 | ring finger protein 208

GeneMGI:1916096Synonyms: 1110061N23Rik

Physiological systems

21 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Endocrine/exocrine gland Growth/size/body region Liver/biliary system Respiratory system Hematopoietic system Behavior/neurological Cardiovascular system

12 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating alanine transaminase level	1 supporting dataset	Rnf208^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.13x10^-9
enlarged thymus	1 supporting dataset	Rnf208^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Rnf208^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased circulating creatine kinase level	1 supporting dataset	Rnf208^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.67x10^-12
increased grip strength	1 supporting dataset	Rnf208^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.31x10^-5
enlarged gallbladder	1 supporting dataset	Rnf208^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Rnf208^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased lung tissue damping	1 supporting dataset	Rnf208^{em1(IMPC)Ccpcz}	homozygote	Early adult	8.99x10^-5
abnormal lymph node morphology	1 supporting dataset	Rnf208^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Rnf208^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rnf208.

Associated images

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Histopathology

There is no histopathology data found for Rnf208.

IMPC related publications

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External links

No external links available for Rnf208.

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*Rnf208^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Rnf208^{tm236227(L1L2_Bact_P)}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector

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