Zc3hc1 | zinc finger, C3HC type 1

GeneMGI:1916023Synonyms: HSPC216, 1110054L24Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Reproductive system Adipose tissue Growth/size/body region Vision/eye Behavior/neurological Skeleton Craniofacial Cardiovascular system

12 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased body weight	4 supporting datasets	Zc3hc1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.65x10^-9
abnormal cornea morphology	1 supporting dataset	Zc3hc1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	2.91x10^-5
abnormal tooth morphology	1 supporting dataset	Zc3hc1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.52x10^-5
decreased lean body mass	1 supporting dataset	Zc3hc1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	4.63x10^-7
abnormal cranium morphology	1 supporting dataset	Zc3hc1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.83x10^-5
male infertility	1 supporting dataset	Zc3hc1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal posture	1 supporting dataset	Zc3hc1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.53x10^-5
increased heart weight	1 supporting dataset	Zc3hc1^{tm1a(KOMP)Wtsi}	heterozygote	Early adult	1.22x10^-5
increased total body fat amount	1 supporting dataset	Zc3hc1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.35x10^-10
abnormal snout morphology	1 supporting dataset	Zc3hc1^{tm1a(KOMP)Wtsi}	homozygote	Early adult	1.72x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zc3hc1.

Associated images

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Histopathology

There is no histopathology data found for Zc3hc1.

IMPC related publications

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External links

No external links available for Zc3hc1.

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*Zc3hc1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Zc3hc1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Zc3hc1^{tm295765(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Zc3hc1^{tm37311(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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