Ifitm1 | interferon induced transmembrane protein 1

GeneMGI:1915963Synonyms: 1110036C17Rik, fragilis2, +1 more

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Growth/size/body region Limbs/digits/tail Hematopoietic system Skeleton Craniofacial Cardiovascular system

16 No significant impact

2 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

long tibia1 supporting datasetIfitm1tm1b(EUCOMM)WtsihomozygoteEarly adult2.9x10-5 
decreased heart weight1 supporting datasetIfitm1not yet assignedhomozygoteEarly adult2.37x10-5 
increased mean corpuscular hemoglobin concentration1 supporting datasetIfitm1not yet assignedhomozygoteEarly adult4.39x10-5 
decreased bone mineral content1 supporting datasetIfitm1tm1b(EUCOMM)WtsihomozygoteLate adult3.6x10-5 
increased lean body mass1 supporting datasetIfitm1tm1b(EUCOMM)WtsihomozygoteEarly adult4.36x10-5 
abnormal snout morphology1 supporting datasetIfitm1tm1b(EUCOMM)WtsihomozygoteLate adult5.38x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ifitm1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Ifitm1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ifitm1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Ifitm1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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