Rgp1 | RAB6A GEF compex partner 1

GeneMGI:1915956Synonyms: 1110029E03Rik

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Nervous system Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

33Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased thigmotaxis	2 supporting datasets	Rgp1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.19x10^-6
decreased circulating calcium level	1 supporting dataset	Rgp1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	7.26x10^-21
decreased circulating glucose level	1 supporting dataset	Rgp1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	5.67x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Rgp1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
decreased circulating cholesterol level	1 supporting dataset	Rgp1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.17x10^-5
embryonic lethality prior to tooth bud stage	1 supporting dataset	Rgp1^{tm1.1(KOMP)Vlcg}	homozygote	E12.5	N/A ^*
abnormal spinal cord morphology	1 supporting dataset	Rgp1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
abnormal behavior	1 supporting dataset	Rgp1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.19x10^-6
embryonic lethality prior to organogenesis	1 supporting dataset	Rgp1^{tm1.1(KOMP)Vlcg}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rgp1.

Associated images

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Histopathology

There is no histopathology data found for Rgp1.

IMPC related publications

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External links

No external links available for Rgp1.

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*Rgp1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Rgp1^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Rgp1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Rgp1^{tm450363(L1L2_GT2_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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