Hddc3 | HD domain containing 3

GeneMGI:1915945Synonyms: 1110033O09Rik

Physiological systems

21 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Liver/biliary system Hematopoietic system Renal/urinary system

13 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal pancreas morphology	1 supporting dataset	Hddc3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased circulating alanine transaminase level	1 supporting dataset	Hddc3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.64x10^-28
male infertility	1 supporting dataset	Hddc3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Hddc3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Hddc3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Hddc3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased circulating aspartate transaminase level	1 supporting dataset	Hddc3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.18x10^-16
abnormal liver morphology	1 supporting dataset	Hddc3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Hddc3.

Associated images

Loading...

Histopathology

There is no histopathology data found for Hddc3.

IMPC related publications

Loading...

External links

No external links available for Hddc3.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Hddc3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Hddc3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Hddc3^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Hddc3^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

My Genes