Kansl1l | KAT8 regulatory NSL complex subunit 1-like

GeneMGI:1915941Synonyms: C430010P07Rik, 1110028C15Rik

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Vision/eye Cardiovascular system

17 No significant impact

3 Not tested

Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased total retina thickness2 supporting datasetsKansl1ltm1b(EUCOMM)WtsihomozygoteEarly adult7.78x10-17 
abnormal retina vasculature morphology1 supporting datasetKansl1ltm1b(EUCOMM)WtsihomozygoteEarly adult4.39x10-6 
abnormal retina morphology1 supporting datasetKansl1ltm1b(EUCOMM)WtsihomozygoteEarly adult8.18x10-7 
abnormal lens morphology1 supporting datasetKansl1ltm1b(EUCOMM)WtsihomozygoteEarly adult1.16x10-12 
persistence of hyaloid vascular system1 supporting datasetKansl1ltm1b(EUCOMM)WtsihomozygoteEarly adult5.72x10-7 
small testis1 supporting datasetKansl1ltm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
enlarged testis1 supporting datasetKansl1ltm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kansl1ltm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Kansl1ltm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Kansl1ltm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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