Arb2a | ARB2 cotranscriptional regulator A

GeneMGI:1915925Synonyms: Fam172a, 53-E6, +4 more

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Endocrine/exocrine gland Liver/biliary system Hematopoietic system Behavior/neurological

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating aspartate transaminase level	1 supporting dataset	Arb2a^{em2(IMPC)Ccpcz}	homozygote	Early adult	4.59x10^-5
decreased Ly6C-positive NK T cell number	1 supporting dataset	Arb2a^{em2(IMPC)Ccpcz}	homozygote	Early adult	1.2x10^-7
abnormal liver morphology	1 supporting dataset	Arb2a^{em2(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Arb2a^{em2(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Arb2a^{em2(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal freezing behavior	1 supporting dataset	Arb2a^{em2(IMPC)Ccpcz}	homozygote	Early adult	3.59x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Arb2a.

Associated images

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Histopathology

There is no histopathology data found for Arb2a.

IMPC related publications

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External links

No external links available for Arb2a.

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*Arb2a^{em1(IMPC)Mhzh}*	Indel	‌	mouse
*Arb2a^{em2(IMPC)Ccpcz}*	Indel	‌	mouse

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