Mthfd2l | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like

GeneMGI:1915871Synonyms: C630010D07Rik, 1110019K23Rik

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Integument Growth/size/body region Cardiovascular system

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged heart	1 supporting dataset	Mthfd2l^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Mthfd2l^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mthfd2l.

Associated images

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Histopathology

There is no histopathology data found for Mthfd2l.

IMPC related publications

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External links

No external links available for Mthfd2l.

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*Mthfd2l^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Mthfd2l^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Mthfd2l^{tm1c(EUCOMM)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse
*Mthfd2l^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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