Dnajc8 | DnaJ heat shock protein family (Hsp40) member C8

GeneMGI:1915848Synonyms: 1110021D09Rik, 2010009J04Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Hematopoietic system Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



prenatal lethality prior to heart atrial septation	1 supporting dataset	Dnajc8^{tm1b(KOMP)Wtsi}	homozygote	E15.5	N/A ^*
increased mean corpuscular hemoglobin	1 supporting dataset	Dnajc8^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	6.69x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Dnajc8^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dnajc8.

Associated images

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Histopathology

There is no histopathology data found for Dnajc8.

IMPC related publications

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External links

No external links available for Dnajc8.

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*Dnajc8^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Dnajc8^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes