Cthrc1 | collagen triple helix repeat containing 1

GeneMGI:1915838Synonyms: 1110014B07Rik

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Vision/eye Liver/biliary system Renal/urinary system

15 No significant impact

4 Not tested

Gene metrics:9Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal kidney morphology1 supporting datasetCthrc1em1(IMPC)MbphomozygoteEarly adultN/A * 
persistence of hyaloid vascular system1 supporting datasetCthrc1em1(IMPC)MbphomozygoteEarly adult7.85x10-6 
abnormal testis morphology1 supporting datasetCthrc1em1(IMPC)MbphomozygoteEarly adultN/A * 
small liver1 supporting datasetCthrc1em1(IMPC)MbphomozygoteEarly adultN/A * 
small kidney1 supporting datasetCthrc1em1(IMPC)MbphomozygoteEarly adultN/A * 
small testis1 supporting datasetCthrc1em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal vitreous body morphology1 supporting datasetCthrc1em1(IMPC)MbphomozygoteEarly adult7.3x10-5 
cataract1 supporting datasetCthrc1em1(IMPC)MbphomozygoteEarly adult9.23x10-5 
abnormal liver morphology1 supporting datasetCthrc1em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cthrc1em1(IMPC)MbpInter-exon deletionmouse
Cthrc1tm102929(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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