Tmed10 | transmembrane p24 trafficking protein 10

GeneMGI:1915831Synonyms: p23, p24delta1, +1 more

Physiological systems

22 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Endocrine/exocrine gland Nervous system Mortality/aging Renal/urinary system

17 No significant impact

2 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
39Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsTmed10tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetTmed10tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetTmed10tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
hydrocephaly1 supporting datasetTmed10tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
small testis1 supporting datasetTmed10tm1.1(KOMP)VlcgheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tmed10tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Tmed10tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Tmed10tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tmed10tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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