Evc2 | EvC ciliary complex subunit 2

GeneMGI:1915775Synonyms: limbin, Ellis van Creveld syndrome 2, +1 more

Physiological systems

20 / 24 physiological systems tested

15 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Digestive/alimentary Hematopoietic system Craniofacial Cardiovascular system Homeostasis/metabolism Nervous system Vision/eye Liver/biliary system Behavior/neurological Skeleton

5 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased prepulse inhibition	5 supporting datasets	Evc2^em1(IMPC)Mbp	homozygote	Early adult	1.32x10^-7
abnormal skin morphology	1 supporting dataset	Evc2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
small spleen	1 supporting dataset	Evc2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
eye hemorrhage	1 supporting dataset	Evc2^em1(IMPC)Mbp	homozygote	Early adult	8.85x10^-5
decreased grip strength	1 supporting dataset	Evc2^em1(IMPC)Mbp	homozygote	Early adult	7.04x10^-5
abnormal gallbladder morphology	1 supporting dataset	Evc2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal snout morphology	1 supporting dataset	Evc2^em1(IMPC)Mbp	homozygote	Early adult	8.4x10^-5
abnormal cecum morphology	1 supporting dataset	Evc2^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased blood urea nitrogen level	1 supporting dataset	Evc2^em1(IMPC)Mbp	homozygote	Early adult	9.26x10^-5
decreased body length	1 supporting dataset	Evc2^em1(IMPC)Mbp	homozygote	Early adult	1.78x10^-12

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Evc2.

Associated images

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Histopathology

There is no histopathology data found for Evc2.

IMPC related publications

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External links

No external links available for Evc2.

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*Evc2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Evc2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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