Ciao2b | cytosolic iron-sulfur assembly component 2B

GeneMGI:1915773Synonyms: Fam96b, 1110019N10Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Immune system Integument Growth/size/body region Hematopoietic system Cardiovascular system Mortality/aging

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal heart morphology	1 supporting dataset	Ciao2b^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
increased neutrophil cell number	1 supporting dataset	Ciao2b^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.28x10^-5
abnormal spleen morphology	2 supporting datasets	Ciao2b^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Ciao2b^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
increased spleen weight	1 supporting dataset	Ciao2b^{em1(IMPC)Ccpcz}	heterozygote	Early adult	5.73x10^-5
enlarged heart	1 supporting dataset	Ciao2b^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Ciao2b^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Ciao2b^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Ciao2b^{em1(IMPC)Ccpcz}	homozygote	E12.5	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Ciao2b^{em1(IMPC)Ccpcz}	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Ciao2b.

Associated images

Loading...

Histopathology

There is no histopathology data found for Ciao2b.

IMPC related publications

Loading...

External links

No external links available for Ciao2b.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Ciao2b^{em1(IMPC)Ccpcz}*	Whole-gene deletion	‌	mouse
*Ciao2b^{tm96914(L1L2_Bact_P)}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector

My Genes