Ppfia4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4

GeneMGI:1915757Synonyms: Gm3812, Liprin-alpha4, +2 more

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Behavior/neurological

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



impaired righting response	1 supporting dataset	Ppfia4^em1(IMPC)Bay	homozygote	Late adult	2.28x10^-5
abnormal behavior	1 supporting dataset	Ppfia4^em1(IMPC)Bay	homozygote	Late adult	5.86x10^-5
decreased exploration in new environment	1 supporting dataset	Ppfia4^em1(IMPC)Bay	homozygote	Early adult	6.47x10^-5
increased cornea thickness	1 supporting dataset	Ppfia4^em1(IMPC)Bay	homozygote	Early adult	5.11x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ppfia4.

Associated images

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Histopathology

There is no histopathology data found for Ppfia4.

IMPC related publications

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External links

No external links available for Ppfia4.

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*Ppfia4^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Ppfia4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ppfia4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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