Bpnt2 | 3'(2'), 5'-bisphosphate nucleotidase 2

GeneMGI:1915720Synonyms: gPAPP, 1110001C20Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Growth/size/body region Behavior/neurological Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetBpnt2tm1a(KOMP)WtsihomozygoteEarly adultN/A * 
increased body weight2 supporting datasetsBpnt2tm1a(KOMP)WtsiheterozygoteEarly adult2.67x10-5 
abnormal gait1 supporting datasetBpnt2tm1a(KOMP)WtsiheterozygoteEarly adult9.21x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bpnt2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Bpnt2tm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Bpnt2tm355870(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Bpnt2tm35826(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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