Tmem129 | transmembrane protein 129

GeneMGI:1915616Synonyms: 0610039G24Rik, 2410015J15Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological

12 No significant impact

7 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues

Phenotypes

increased total body fat amount2 supporting datasetsTmem129tm1.1(KOMP)VlcghomozygoteEarly adult1.42x10-6 
hyperactivity1 supporting datasetTmem129tm1.1(KOMP)VlcghomozygoteEarly adult6.65x10-5 
decreased mean corpuscular hemoglobin concentration1 supporting datasetTmem129tm1.1(KOMP)VlcghomozygoteEarly adult3.06x10-5 
increased circulating alkaline phosphatase level1 supporting datasetTmem129tm1.1(KOMP)VlcghomozygoteEarly adult1.44x10-5 
decreased lean body mass2 supporting datasetsTmem129tm1.1(KOMP)VlcghomozygoteEarly adult3.27x10-6 
increased circulating HDL cholesterol level1 supporting datasetTmem129tm1.1(KOMP)VlcghomozygoteEarly adult7.52x10-5 
increased circulating cholesterol level1 supporting datasetTmem129tm1.1(KOMP)VlcghomozygoteEarly adult1.17x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tmem129tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Tmem129tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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