Babam1 | BRISC and BRCA1 A complex member 1

GeneMGI:1915501Synonyms: 5430437P03Rik

Physiological systems

21 / 24 physiological systems tested

11 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Endocrine/exocrine gland Growth/size/body region Muscle Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Cardiovascular system Renal/urinary system

10 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:18Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



impaired contextual conditioning behavior	1 supporting dataset	Babam1^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.15x10^-6
increased eosinophil cell number	1 supporting dataset	Babam1^{em1(IMPC)Ccpcz}	homozygote	Early adult	5.54x10^-8
increased circulating alanine transaminase level	1 supporting dataset	Babam1^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.42x10^-5
abnormal kidney morphology	1 supporting dataset	Babam1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Babam1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal eye morphology	1 supporting dataset	Babam1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Babam1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased freezing behavior	1 supporting dataset	Babam1^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.44x10^-8
increased liver weight	1 supporting dataset	Babam1^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.35x10^-5
impaired cued conditioning behavior	1 supporting dataset	Babam1^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.01x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Babam1.

Associated images

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Histopathology

There is no histopathology data found for Babam1.

IMPC related publications

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External links

No external links available for Babam1.

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*Babam1^{em1(IMPC)Ccpcz}*	Inter-exon deletion	‌	mouse
*Babam1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Babam1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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