Tecr | trans-2,3-enoyl-CoA reductase

GeneMGI:1915408Synonyms: 2410016D23Rik, SC2, +3 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Endocrine/exocrine gland Digestive/alimentary Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal stomach morphology	2 supporting datasets	Tecr^{em1(IMPC)Rbrc}	heterozygote	Late adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Tecr^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*
increased circulating LDL cholesterol level	1 supporting dataset	Tecr^{em1(IMPC)Rbrc}	heterozygote	Early adult	3.8x10^-5
abnormal pancreas morphology	1 supporting dataset	Tecr^{em1(IMPC)Rbrc}	heterozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tecr.

Associated images

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Histopathology

There is no histopathology data found for Tecr.

IMPC related publications

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External links

No external links available for Tecr.

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*Tecr^{em1(IMPC)Rbrc}*	Exon Deletion	‌	mouse
*Tecr^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Tecr^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tecr^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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