Gtf2e2 | general transcription factor II E, polypeptide 2 (beta subunit)
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Mortality/aging
16 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
21Embryo tissues
| increased circulating creatinine level | 1 supporting dataset | Gtf2e2tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 4.89x10-6 | ||
| increased mean platelet volume | 1 supporting dataset | Gtf2e2tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 2.16x10-5 | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Gtf2e2tm1b(EUCOMM)Wtsi | homozygote | E12.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Gtf2e2tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Gtf2e2tm1b(EUCOMM)Wtsi | homozygote | E9.5 | N/A * |
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External links
No external links available for Gtf2e2.
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| Gtf2e2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Gtf2e2tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Gtf2e2tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |