Tox4 | TOX high mobility group box family member 4
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| decreased circulating glucose level | 1 supporting dataset | Tox4tm1b(KOMP)Mbp | heterozygote | Early adult | 1.28x10-5 | ||
| increased circulating creatinine level | 1 supporting dataset | Tox4tm1b(KOMP)Mbp | heterozygote | Early adult | 4.16x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Tox4tm1b(KOMP)Mbp | homozygote | Early adult | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Tox4tm1b(KOMP)Mbp | homozygote | E12.5 | N/A * |
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External links
No external links available for Tox4.
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| Tox4tm1a(KOMP)Mbp | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Tox4tm1b(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Tox4tm1e(KOMP)Mbp | Targeted, non-conditional allele | | ES Cell |