Pwwp3a | PWWP domain containing 3A, DNA repair factor

GeneMGI:1915364Synonyms: 9430059D04Rik, Mum1

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Endocrine/exocrine gland Hematopoietic system Behavior/neurological

13 No significant impact

6 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased vertical activity1 supporting datasetPwwp3aem1(IMPC)TcphomozygoteEarly adult5.2x10-5 
hyperactivity4 supporting datasetsPwwp3aem1(IMPC)TcphomozygoteEarly adult7.96x10-16 
small thymus1 supporting datasetPwwp3aem1(IMPC)TcphomozygoteEarly adultN/A * 
increased blood urea nitrogen level1 supporting datasetPwwp3aem1(IMPC)TcphomozygoteEarly adult7.47x10-5 
thrombocytosis1 supporting datasetPwwp3aem1(IMPC)TcphomozygoteEarly adult7.38x10-5 
decreased circulating alkaline phosphatase level1 supporting datasetPwwp3aem1(IMPC)TcphomozygoteEarly adult5.58x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pwwp3aem1(IMPC)TcpExon Deletionmouse

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