Smarcc2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

GeneMGI:1915344Synonyms: 5930405J04Rik

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Hearing/vestibular/ear Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Smarcc2^em1(IMPC)J	homozygote	Early adult	N/A ^*
decreased thigmotaxis	2 supporting datasets	Smarcc2^em1(IMPC)J	heterozygote	Early adult	4.05x10^-5
decreased heart rate	1 supporting dataset	Smarcc2^em1(IMPC)J	heterozygote	Early adult	1.48x10^-6
prolonged RR interval	1 supporting dataset	Smarcc2^em1(IMPC)J	heterozygote	Early adult	1.72x10^-6
increased mean corpuscular volume	1 supporting dataset	Smarcc2^em1(IMPC)J	heterozygote	Early adult	3.66x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Smarcc2.

Associated images

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Histopathology

There is no histopathology data found for Smarcc2.

IMPC related publications

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External links

No external links available for Smarcc2.

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*Smarcc2^em1(IMPC)J*	Exon Deletion	‌	mouse
*Smarcc2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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