Arpc4 | actin related protein 2/3 complex, subunit 4

GeneMGI:1915339Synonyms: p20-Arc, 5330419I20Rik

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Integument Hematopoietic system Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal hair texture	1 supporting dataset	Arpc4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.14x10^-5
increased mean corpuscular hemoglobin	1 supporting dataset	Arpc4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	9.43x10^-7
increased leukocyte cell number	1 supporting dataset	Arpc4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.35x10^-6
increased mean corpuscular volume	1 supporting dataset	Arpc4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	3.29x10^-7
preweaning lethality, complete penetrance	1 supporting dataset	Arpc4^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Arpc4.

Associated images

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Histopathology

There is no histopathology data found for Arpc4.

IMPC related publications

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External links

No external links available for Arpc4.

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*Arpc4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse

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